BioLegend 348104 PE anti-human

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BioLegend 348104 PE anti-human TCR Vβ8
产品简介：
产品品牌：BioLegend
产品货号：348104
产品名称：BioLegend 348104 PE anti-human TCR Vβ8
产品规格：100 tests   

产品说明：
Clone   JR2 (JR.2) (See other available formats)
Regulatory Status   RUO
Other Names   Vbeta8
Isotype   Mouse IgG2b, κ

描述
Vβ8 T细胞受体（TCR Vβ8）是TCR β链的变体，其与TCR α链异二聚化并在T细胞亚群上表达。与CD3复合物相关，TCR α/β功能识别抗原并启动T细胞介导的免疫反应。人 Vβ8 已被描述为链球菌有丝分裂外毒素 z （SMEZ） 和 SMEZ-2 的靶标。
Vβ8 T cell receptor (TCR Vβ8) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of T cells. In association with CD3 complex, TCR α/β functions recognition of antigen and initiating T cell mediated immune responses. Human Vβ8 has been described as the target of the streptococcal mitogenic exotoxin z (SMEZ) and SMEZ-2.

Product Details
Isotype Control   PE Mouse IgG2b, κ Isotype Ctrl
Verified Reactivity   Human
Antibody Type   Monoclonal
Host Species   Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.

Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application   FC - Quality tested

Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser  Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Antigen Details
Structure
Immunoglobulin superfamily, associate with TCR Vα chain and CD3 complex
Distribution   Subset of T cells
Function   Antigen recognition
Ligand/Receptor   MHC-Peptide complex
Cell Type   T cells
Biology Area   Adaptive Immunity, Immunology
Molecular Family   TCRs

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