BioLegend 309404 PE anti-human CD275 (B7-H2, ICOSL) 产品简介: 产品品牌:BioLegend 产品货号:309404 产品名称:BioLegend 309404 PE anti-human CD275 (B7-H2, ICOSL) 产品规格:100 tests
产品说明: Clone 2D3 (See other available formats) Regulatory Status RUO Other Names CD275, ICOSL, B7H2, ICOS-L, B7RP-1, B7-RP1 Isotype Mouse IgG2b, κ
描述 B7-H2是B7家族和免疫球蛋白超家族的成员,是一种40 kD蛋白,也称为B7RP-1,B7h,B7-H2,GL50和ICOS配体。人 B7-H2 由 B 淋巴细胞、活化的单核细胞/巨噬细胞和树突状细胞表达。B7-H2与CD28样受体结合,诱导性共刺激分子(ICOS,AILIM,CRP-1),其由活化的T细胞表达。ICOS与B7-H2的相互作用在T细胞共刺激途径中起重要作用。 B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by B lymphocytes, activated monocytes/macrophages, and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway.
Product Details Isotype Control PE Mouse IgG2b, κ Isotype Ctrl Verified Reactivity Human Antibody Type Monoclonal Host Species Mouse Immunogen Human B7H2-mIg fusion protein Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) Preparation The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. Concentration Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.) Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. Application FC - Quality tested
Recommended Usage Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser Blue Laser (488 nm) Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Antigen Details Structure Ig superfamily, B7 family, 40 kD Distribution B cells and dendritic cells Function Binds ICOS on antigen-activated T cells and mediates proliferation and cytokine production Ligand/Receptor ICOS Cell Type B cells, Dendritic cells Biology Area Costimulatory Molecules, Immunology Molecular Family CD Molecules
以下是 BioLegend 品牌部分产品,如需其他产品请联系本公司销售。 BioLegend 148216 Brilliant Violet 421™ anti-mouse/rat XCR1 ZET 50 ug BioLegend 148218 Brilliant Violet 510™ anti-mouse/rat XCR1 ZET 50 ug BioLegend 148220 Brilliant Violet 650™ anti-mouse/rat XCR1 ZET 50 ug BioLegend 148224 APC/Cyanine7 anti-mouse/rat XCR1 ZET 100 ug BioLegend 148303 APC anti-mouse/rat CD62P (P-selectin) RMP-1 25 ug BioLegend 148304 APC anti-mouse/rat CD62P (P-selectin) RMP-1 100 ug BioLegend 148305 PE anti-mouse/rat CD62P (P-selectin) RMP-1 25 ug BioLegend 148306 PE anti-mouse/rat CD62P (P-selectin) RMP-1 100 ug BioLegend 148503 PE anti-mouse/rat CD42d 1C2 25 ug BioLegend 148504 PE anti-mouse/rat CD42d 1C2 100 ug BioLegend 148506 APC anti-mouse/rat CD42d 1C2 100 ug BioLegend 148508 PerCP/Cyanine5.5 anti-mouse/rat CD42d 1C2 100 ug BioLegend 148601 Purified anti-mouse CD282 (TLR2) CB225 50 ug BioLegend 148603 PE anti-mouse CD282 (TLR2) CB225 25 ug BioLegend 148703 PE anti-mouse P2X7R 1F11 25 ug BioLegend 149002 Purified anti-mouse CX3CR1 SA011F11 100 ug BioLegend 149004 Alexa Fluor® 647 anti-mouse CX3CR1 SA011F11 100 ug BioLegend 149005 PE anti-mouse CX3CR1 SA011F11 25 ug BioLegend 149006 PE anti-mouse CX3CR1 SA011F11 100 ug BioLegend 149007 APC anti-mouse CX3CR1 SA011F11 25 ug BioLegend 149008 APC anti-mouse CX3CR1 SA011F11 100 ug BioLegend 149009 PerCP/Cyanine5.5 anti-mouse CX3CR1 SA011F11 25 ug