BioLegend 303121 Brilliant Vio

北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。

美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。

BioLegend 303121 Brilliant Violet 605™ anti-human CD31
产品简介：
产品品牌：BioLegend
产品货号：303121
产品名称：BioLegend 303121 Brilliant Violet 605™ anti-human CD31
产品规格：25 tests

产品说明：
Clone  WM59 (See other available formats)
Regulatory Status  RUO
Workshop  V P025
Other Names  PECAM-1, EndoCAM
Isotype  Mouse IgG1, κ

描述
CD31 是一种 130-140 kD 的 I 型跨膜糖蛋白，也称为血小板内皮细胞粘附分子-1 （PECAM-1） 或 Endocam。它在单核细胞、血小板、粒细胞、内皮细胞和淋巴细胞亚群中表达。据报道，CD31 可结合 CD38 并在炎症情况下参与伤口愈合、血管生成和细胞迁移。
CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.

Product Details
Isotype Control  Brilliant Violet 605™ Mouse IgG1, κ Isotype Ctrl
Verified Reactivity  Human, Cynomolgus, Rhesus
Reported Reactivity  African Green, Baboon
Antibody Type  Monoclonal
Host Species  Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605™ under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application  FC - Quality tested

Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Brilliant Violet 605™ excites at 405 nm and emits at 603 nm. The bandpass filter 610/20 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 605™ is a trademark of Sirigen Group Ltd.

Learn more about Brilliant Violet™.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Excitation Laser  Violet Laser (405 nm)
Application Notes
Clone WM59 has been reported to recognize the D2 extracellular portion of CD31.

Additional reported applications (for the relevant formats) include: immunofluorescence microscopy2, immunohistochemical staining of *-fixed frozen tissue sections8, blocking of platelet aggregation3, and spatial biology (IBEX)11,12. Clone WM59 is not recommended for immunohistochemical staining of formalin-fixed paraffin-embedded sections. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 303143 & 303144).

The purified WM59 antibody is useful as a capture antibody for a sandwich ELISA assay, when used in conjunction with biotin anti-human CD31 antibody (Cat. No. 536604) antibody as the detection antibody.

Antigen Details
Structure
Ig superfamily, type I transmembrane glycoprotein, 130-140 kD
Distribution
Monocytes, platelets, granulocytes, endothelial cells, lymphocyte subset

Function  Cell adhesion, signal transduction
Ligand/Receptor  CD38
Cell Type
Endothelial cells, Granulocytes, Lymphocytes, Monocytes, Neutrophils, Platelets
Biology Area
Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family   Adhesion Molecules, CD Molecules

以下是 BioLegend 品牌部分产品，如需其他产品请联系本公司销售。
BioLegend 144001 Purified anti-mouse CD172a (SIRPα) P84      50 ug
BioLegend 144002 Purified anti-mouse CD172a (SIRPα) P84      500 ug
BioLegend 144005 FITC anti-mouse CD172a (SIRPα) P84      25 ug
BioLegend 144006 FITC anti-mouse CD172a (SIRPα) P84      100 ug
BioLegend 144007 PE/Cyanine7 anti-mouse CD172a (SIRPα)     P84      25 ug
BioLegend 144009 PerCP/Cyanine5.5 anti-mouse CD172a (SIRPα)  P84      25 ug
BioLegend 144010 PerCP/Cyanine5.5 anti-mouse CD172a (SIRPα)  P84      100 ug
BioLegend 144011 PE anti-mouse CD172a (SIRPα)   P84      25 ug
BioLegend 144012 PE anti-mouse CD172a (SIRPα)   P84      100 ug
BioLegend 144013 APC anti-mouse CD172a (SIRPα) P84      25 ug
BioLegend 144015 PE/Dazzle™ 594 anti-mouse CD172a (SIRPα)     P84      25 ug
BioLegend 144016 PE/Dazzle™ 594 anti-mouse CD172a (SIRPα)     P84      100 ug
BioLegend 144017 APC/Cyanine7 anti-mouse CD172a (SIRPα)  P84      25 ug
BioLegend 144018 APC/Cyanine7 anti-mouse CD172a (SIRPα)  P84      100 ug
BioLegend 144021 Alexa Fluor® 700 anti-mouse CD172a (SIRPα)   P84      25 ug
BioLegend 144022 Alexa Fluor® 700 anti-mouse CD172a (SIRPα)   P84      100 ug
BioLegend 144032 Brilliant Violet 510™ anti-mouse CD172a (SIRPα)     P84      50 ug
BioLegend 144036 Ultra-LEAF™ Purified anti-mouse CD172a (SIRPα)    P84      1 mg
BioLegend 144103 PE anti-mouse PIR-A/B    6C1     25 ug
BioLegend 144202 Purified anti-mouse/human CD207 (Langerin)   4C7     100 ug
BioLegend 144204 PE anti-mouse/human CD207 (Langerin)      4C7     100 ug
BioLegend 144205 APC anti-mouse/human CD207 (Langerin)   4C7     25 ug