BioLegend 148508 PerCP/Cyanine

北京云肽生物科技有限公司作为BioLegend的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。

美国BioLegend公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长，但它聚集了一批来自PharMingen公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。

BioLegend 148508 PerCP/Cyanine5.5 anti-mouse/rat CD42d
产品简介：
产品品牌：BioLegend
产品货号：148508
产品名称：BioLegend 148508 PerCP/Cyanine5.5 anti-mouse/rat CD42d
产品规格：100 µg

产品说明：
Clone  1C2 (See other available formats)
Regulatory Status  RUO
Other Names
Platelet glycoprotein V, GPV, platelet gpV, CD42d antigen, CD42d
Isotype  Armenian Hamster IgG

描述
CD42d是一种83kD的表面糖蛋白，与GPIb和GPIX非共价结合，在巨核细胞和静息血小板上形成von Willebrand因子的受体复合物。von Willebrand因子和凝血酶的结合位点已定位于GPI-b-V-IX复合物的GPIba链。用凝血酶活化血小板切割GPI-b-V-IX复合物以释放69kD可溶性片段。GPI-b-V-IX复合物的存在在Bernard-Soulier综合征（一种罕见的出血性疾病）中很重要。
CD42d is an 83 kD surface glycoprotein that non-covalently associates with GPIb and GPIX to form a receptor complex for von Willebrand factor on megakaryocytes and resting platelets. Binding sites for von Willebrand factor and thrombin have been localized to the GPIba chain of the GPI-b-V-IX complex. Platelet activation with thrombin cleaves the GPI-b-V-IX complex to release a 69 kD soluble fragment. Presence of the GPI-b-V-IX complex is important in Bernard-Soulier syndrome, a rare bleeding disorder.

Product Details
Isotype Control
PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Ctrl
Verified Reactivity  Mouse, Rat
Antibody Type  Monoclonal
Host Species  Armenian Hamster
Immunogen  Mouse platelets
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.PreparationThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.Concentration0.2 mg/mlStorage & HandlingThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.Application
FC - Quality tested

Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Application Notes
Additional reported applications (for relevant formats) include: immunoprecipitation1,3.

Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.

Antigen Details
Structure
83 kD heterodimer composed of 2 polypeptide chains, an α chain (GP1BA) and a β chain (GP1BB).
Distribution  Resting platelets and megakaryocytes.
Function
CD42d is a component of the GPIb-V-IX complex, functions as a vWF receptor, and mediates vWF-dependent platelet adhesion to blood vessels.
Ligand/Receptor  CD42d.
Cell Type  Megakaryocytes, Platelets
Biology Area  Cell Adhesion, Cell Biology, Immunology
Molecular Family  Adhesion Molecules, CD Molecules

以下是BioLegend  品牌部分产品，如需其他产品请联系本公司销售。
BioLegend 127416 FITC anti-mouse Podoplanin  8.1.1    100 ug
BioLegend 127417 APC/Cyanine7 anti-mouse Podoplanin   8.1.1    25 ug
BioLegend 127418 APC/Cyanine7 anti-mouse Podoplanin   8.1.1    100 ug
BioLegend 127423 Brilliant Violet 421™ anti-mouse Podoplanin 8.1.1    50 ug
BioLegend 127501 Purified anti-mouse CD47     miap301    50 ug
BioLegend 127503 FITC anti-mouse CD47     miap301    50 ug
BioLegend 127504 FITC anti-mouse CD47     miap301    500 ug
BioLegend 127507 PE anti-mouse CD47  miap301    50 ug
BioLegend 127510 Alexa Fluor® 647 anti-mouse CD47  miap301    100 ug
BioLegend 127513 APC anti-mouse CD47     miap301    25 ug
BioLegend 127514 APC anti-mouse CD47     miap301    100 ug
BioLegend 127526 APC/Cyanine7 anti-mouse CD47 miap301    100 ug
BioLegend 127602 Purified anti-mouse Ly-6G     1A8     500 ug
BioLegend 127605 FITC anti-mouse Ly-6G    1A8     50 ug
BioLegend 127606 FITC anti-mouse Ly-6G    1A8     500 ug
BioLegend 127607 PE anti-mouse Ly-6G  1A8     50 ug
BioLegend 127608 PE anti-mouse Ly-6G  1A8     200 ug
BioLegend 127609 Alexa Fluor® 647 anti-mouse Ly-6G 1A8     25 ug
BioLegend 127610 Alexa Fluor® 647 anti-mouse Ly-6G 1A8     100 ug
BioLegend 127611 Pacific Blue™ anti-mouse Ly-6G  1A8     25 ug
BioLegend 127612 Pacific Blue™ anti-mouse Ly-6G  1A8     100 ug
BioLegend 127613 APC anti-mouse Ly-6G     1A8     25 ug