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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
742058-34-0
- 规格：
25 mg///50 mg///100 mg
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Nurr1 agonist 2
CAS No. : 742058-34-0
MCE 国际站：Nurr1 agonist 2
产品活性：Nurr1 agonist 2 (Compound 7) 是一种 Nurr1 激动剂 (EC50: 0.07 μM)。Nurr1 agonist 2 与重组 Nurr1 配体结合域 (LBD) 结合，Kd 值为 0.14 μM。Nurr1 agonist 2 增加 Nurr1 调节基因酪氨酸羟化酶 (TH) 和囊泡氨基酸转运蛋白 2 (VMAT2) 的 mRNA 表达。
研究领域：Others
作用靶点：Others
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文献和实验[3H](+)MK801 Radioligand Binding Assay at the N‐Methyl‐D‐Aspartate Receptor
?aspartate subtype of glutamate receptor is unusual in that it requires two endogenous agonists for activation. Thus, in addition to glutamate, the amino acid glycine (or possibly D ?serine) is an essential co?agonist. This unit presents a radioligand binding
Overview of Receptor Allosterism
of the myriad of possible allosteric effects on binding and signaling events. This unit provides an overview on GPCR allosterism and the different pharmacological approaches to understanding allosteric behaviors. Curr. Protoc. Pharmacol. 51:1.21.1?1.21.34. ©
and disease. Keywords: agonist; antagonist allosteric modulator; G protein?coupled receptor; heterotrimeric G protein; ion channels; ligand; new chemical entity (NCE); orphan receptor; structure activity relationship (SAR
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