Quinine sulfate奎宁硫酸盐水合物,6119-7

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Quinine sulfate hydrate

CAS No. : 6119-70-6

MCE 国际站：Quinine sulfate hydrate

产品活性：Quinine sulfate hydrate (2:1:4) 是一种从金鸡纳树皮中提取的生物碱，具有口服活性，可用作抗疟疾研究。Quinine sulfate hydrate (2:1:4) 是一种钾离子通道 (potassium channel) 抑制剂，可抑制电压脉冲引起的 MT mSlo3 (K_Ca5.1) 通道 +100 mV 电流, 其 IC₅₀ 值为 169 μM。

研究领域：Anti-infection  |  Membrane Transporter/Ion Channel

作用靶点：Flavivirus  |  Parasite  |  Potassium Channel

In Vitro: Quinine sulfate hydrate (150 μM, 30 min) inhibits the proliferation and cytostatic effects of DENV (Dengue virus) in human hepatocarcinoma HepG2 cell line.
Quinine sulfate hydrate (37.5-150 μM, 24 hours) significantly reduces viral DENV RNA and protein levels in a dose-dependent manner in human hepatocarcinoma HepG2 cell line.

In Vivo: Quinine sulfate hydrate (oral gavage, 12 or 15 mg/kg, every week, 16 weeks) has some tumor suppressing effect on skin cancer in Swiss albino mice.
Quinine sulfate hydrate (oral gavage, 10 mg/kg, everyday, 8 weeks) causes a decrease in the antioxidant defense system of rat testicular tissue such as SOD, CAT and GSH enzyme activity in male adult albino rats.

相关产品：Natural Product Library Plus  |  Drug Repurposing Compound Library Plus  |  FDA-Approved Drug Library Plus  |  FDA-Approved Drug Library Mini  |  Bioactive Compound Library Plus  |  Anti-Infection Compound Library  |  Membrane Transporter/Ion Channel Compound Library  |  Natural Product Library  |  FDA-Approved Drug Library  |  Drug Repurposing Compound Library  |  Orally Active Compound Library  |  FDA Approved & Pharmacopeial Drug Library  |  Anti-Alzheimer's Disease Compound Library  |  Drug-Induced Liver Injury (DILI) Compound Library  |  Antiparasitic Compound library  |  Neurodegenerative Disease-related Compound Library  |  Food Additive Library   |  Children’s Drug Library  |  Potassium Channel Compound Library  |  Off-patent Drug Library  |  Membrane Protein-targeted Compound Library  |  Membrane Receptor-targeted Compound Library  |  Ion Channel Compound Library  |  Chloroquine  |  Puromycin dihydrochloride  |  Nigericin sodium salt  |  Hygromycin B  |  Doxycycline hyclate  |  Yoda 1  |  Acetaminophen  |  Anisomycin  |  BAPTA-AM  |  Emricasan  |  Metronidazole  |  Minocycline hydrochloride  |  Kaempferol  |  Amphotericin B  |  Dihydroartemisinin  |  Branaplam  |  Hydroxychloroquine sulfate  |  Niclosamide  |  Artesunate  |  Berberine chloride  |  Monensin sodium salt  |  Acridine Orange hydrochloride  |  Ivermectin  |  U18666A  |  Eflornithine hydrochloride hydrate  |  Rosuvastatin Calcium  |  Azithromycin

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds