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Please store the product under the recommended conditions in the Certificate of Analysis.
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货期:询盘
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MedChemExpress LLC
- CAS号:
2924546-70-1
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询盘
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SJ1461
CAS No. : 2924546-70-1
MCE 国际站:SJ1461
产品活性:SJ1461 是一种有效的口服活性 BET 抑制剂。SJ1461 抑制 BRD2 (BD1)、BRD2 (BD2)、BRD4 (BD1) 和 BRD4 (BD2),IC50 值分别为 1.6 nM、0.1 nM、6.5 nM 和 0.2 nM。
研究领域:Epigenetics
作用靶点:Epigenetic Reader Domain
In Vitro: SJ1461 inhibits cancer cells growth of MV4-11, NALM-16, MOLM-13, HDMB03, and D283 cells, with IC50 values of 20 nM, 3.6 nM, 10.2 nM, 6.6 nM, and 56.2 nM, respectively.
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文献和实验,Gregory B,Hover A,Chen MY,Luci J,Joo SJ,Handwerker D,Liang J,Boyd R,Hunicke- Smith S,Simpson ZB,Caven T, Sochat V,Shine JM,Gordon E,Snyder AZ,Adeyemo B,Petersen SE,Glahn D, McKay DR,Curran JE,Göring HHH,Carless MA,Blangero J,Frick L,Marcotte E, Mumford JA
Transformation Protocol for Arabidopsis
, store at 4°C Selection: • Weigh seed to estimate number (100 seed ≈ 21.8mg) • Sterilise for 2 mins in 70% (v/v) ethanol followed by 20 mins in 20% (v/v) bleach (Zixo brand) + 0.02% Triton X-100. Keep the seeds moving in the bleach solution
Bst-catalyzed radiolabeled DNA sequencing
are stored at -70degC prior to the addition of loading dye. When double-stranded pUC-based subclones are used as templates, the amount of primer is doubled and a denaturing/annealing step is added. Here, 3 ug of plasmid DNA, isolated by either the mini
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