0.2 µm filtered in phosphate-buffered solution, pH 7.4, containing no preservative. Endotoxin level is <0.01 EU/µg
靶标
背景说明
The CD3 protein is a T-cell marker, a complex of four structurally distinct membrane glycoprotein isoforms, 20-50 kDa, comprising extracellular, transmembrane and intracellular domains. CD3 is associated with an heterodimer creating the T-cell receptor (TCR). The CD3 complex is responsible for mediating signal transduction to the internal environment upon antigenic recognition by TCR, causing T-cell proliferation and release of cytokines.
细胞定位
Cell membrane
UniProt
P24161
实验结果图:
Flow cytometric analysis of Mouse blood cells labelling CD3 antibody at 1/500 (0.1 μg) dilution/ (red) compared with a Rat monoclonal IgG (Black) isotype control . Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody.
Flow cytometric analysis of Mouse splenocytes labelling CD3 antibody at 1/500 (0.1 μg) dilution/ (red) compared with a Rat monoclonal IgG (Black) isotype control . Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody.