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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Virus-Like Particles (VLPs) isotype control
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Virus-Like Particles (VLPs) isotype control品名简称:
VLPs isotype control货号:
CSB-MP3838规格:
20μg价格:
804LC-MS/Western Blot:
/SDS-PAGE:
/纯度:
The purity information is not available for VLPs proteins.内毒素:
Not test生物活性:
/基因名:
N/AUniprot No.:
/别名:
/种属:
N/A蛋白长度:
Full Length来源:
Mammalian cell分子量:
56.1 kDa表达区域:
/氨基酸序列:
/蛋白标签:
Tag-Free产品提供形式:
Lyophilized powder缓冲液:
Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex.Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).功能1:
/功能2:
/文献:
/研究领域:
/请点击“在线询价”找客服索取产品说明书及引用文献目录,产品实时更新参数、价格信息、更多文献信息可以查看cusabio官网
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文献和实验的作用是调控基因表达。例如组蛋白甲基化多导致基因沉默,去甲基化则相反;乙酰化一般是转录激活,去乙酰化则相反。当然,也可在此基础上产生复杂的生物学效应。例如组蛋白去乙酰化酶 HDAC 可影响免疫系统;H3K4me3、H3K9me2 能够调控记忆的形成, 而且 H3K 甲基化与 X 染色体失活、基因组印记和异染色质形成有关;H3 乙酰化通过多种机制调控以来 ATP 的染色质重塑 ,并参与炎症反应;H2A、H2B 泛素化则与 DNA 损害反应有关;而 H3S28 磷酸化与 H3K27 乙酰化可激活转录
基因编辑再次升级!领域大牛刘如谦 Cell 发文开发新工具,可安全高效进行体内基因编辑
的 VLPs 策略的编辑效率比较一般,且体内治疗效果的验证有限。 2022 年 1 月 11 日,哈佛大学刘如谦团队在国际顶尖期刊 Cell 发表了题为 Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins 的研究性文章,报道了一种他们以逆转录病毒为基础而开发的工程化类病毒颗粒(Engineered virus-like particles,eVLP),它能够克服蛋白复合物递送的多个瓶颈
Transcriptional Control of Hepatitis B Virus
Hepatitis B virus (HBV) transcriptional regulation has been extensively studied in vitro by transient transfection using the activity of a reporter molecule as the readout for transcriptional activity (1 –5 ). Several reporter molecules
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