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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃/-80℃
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Fragile X mental retardation syndrome-related protein 1 (FXR1), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
1mg/100ug/20ug
| 规格: | 1mg | 产品价格: | ¥14796.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥3468.0 |
| 规格: | 20ug | 产品价格: | ¥1836.0 |
Research Areas
Epigenetics and Nuclear SignalingUniprot ID
P51114Gene Names
FXR1Alternative Name(s)
(FMR1 autosomal homolog 1)(hFXR1p)Lead Time
3-7 business daysOrganism
Homo sapiens (Human)Source
E.coliExpression Region
218-280aaProtein Length
PartialTag Info
C-terminal 6xHis-taggedTarget Protein Sequence
AFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEMW
7.8 kDaPurity
Greater than 90% as determined by SDS-PAGE.Endotoxin
Not test.Biological_Activity
/Form
Liquid or Lyophilized powderBuffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.Relevance
RNA-binding protein required for embryonic and postnatal development of muscle tissue . May regulate intracellular transport and local translation of certain mRNAs .Function
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文献和实验三句话读懂一篇 CNS:昼夜颠倒的睡眠,容易加速肥胖;为什么思考会让人感到疲惫?
translation of stored mRNAs。 该研究发现 RNA 结合蛋白 FXR1 是介导 mRNA 翻译激活的关键蛋白,可通过液液相分离激活小鼠后期精子细胞中 mRNA 的翻译,保障精子形成过程的正常进行! 图 5:来源 Science 6. Nature:非经典维生素 K 循环可有效抑制铁死亡 铁死亡作为一种非凋亡性细胞死亡形式,在器官损伤、退行性疾病和耐药性癌症的易感性中起关键作用。 2022 年 8 月 3 日,德国代谢和细胞死亡研究所 Marcus Conrad 团队
玉米Proline responding 1(pro1)突变在蛋白合成和细胞周期调控中起到关键作用
),它是催化以谷氨酸为前体合成脯氨酸过程中的限速酶(Figure 2B, C, D, E)。Pro1基因功能的丧失,造成突变体中脯氨酸合成与积累的下降。Figure 2Phylogenetic Analysis of Pro1 and Biochemical Assay of Recombinant P5CS Protein.(A) Phylogenetic relationships of Pro1 (Zm P5CS) and its homologs.Maize Pro1 and identified
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