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人TFPI重组蛋白(TFPI)(Extrinsic path

way inhibitor)(EPI)(Lipoprotein-associated coagulation inhibitor)(LACI)Human Tissue factor pathway inhibitor(TFPI)(Active)蛋白
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  • CSB-MP023437HU
  • 2026年01月20日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Human Tissue factor pathway inhibitor (TFPI), partial (Active)

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      20μg


    英文名称:

    Recombinant Human Tissue factor pathway inhibitor (TFPI), partial (Active)

    品名简称:

    Recombinant Human TFPI protein, partial (Active)

    货号:

    CSB-MP023437HU

    规格:

    20μg

    价格:

    888

    LC-MS/Western Blot:

    /

    SDS-PAGE:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    纯度:

    Greater than 95% as determined by SDS-PAGE.

    内毒素:

    Less than 1.0 EU/μg as determined by LAL method.

    生物活性:

    Measured by its binding ability in a functional ELISA. Immobilized Human TFPI at 1 μg/mL can bind Anti-TFPI recombinant antibody (CSB-RA023437MA01HU), the EC50 is 1.242-1.788 ng/mL.

    基因名:

    TFPI

    Uniprot No.:

    P10646

    别名:

    (TFPI)(Extrinsic pathway inhibitor)(EPI)(Lipoprotein-associated coagulation inhibitor)(LACI)

    种属:

    Homo sapiens (Human)

    蛋白长度:

    Partial

    来源:

    Mammalian cell

    分子量:

    31.9 kDa

    表达区域:

    29-282aa

    氨基酸序列:

    DSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIK

    蛋白标签:

    C-terminal 10xHis-tagged

    产品提供形式:

    Lyophilized powder

    缓冲液:

    Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0

    储存条件:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    保质期:

    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    货期:

    3-7 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能1:

    Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

    功能2:

    /

    文献:

    /

    研究领域:

    Cardiovascular

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    相关实验
    • TFPI的基因工程

      information,NCBl)网站http://www.ncbi.nlm.nih.gov,在Search栏中键人nucleotide,在For栏中键人humanTFPImRNA,点击Go。     (2)网页上会出现许多搜索结果,选择NM-006287 Homo sapiens tissue hctor pathway inhibitor(lipoprotein-associated coagulation inhibitor)(TFPI),transcript variantl,mRNA,即可

    • 组织因子途径抑制物(TFPI) 的结构和功能

      组织因子途径抑制物 (TFPI) 的结构和功能       组织 因子途径抑制物(tissue factor pathway inhibitorTFPI)是外源性凝血途径的天然抑制物,,它能与FXa直接结合并抑制其活性,形成的FXa/TFPI复合物,既可以与启动外源性凝血途径的FVIIa/TF复合物结合,同时可抑制其活性,从根本上阻止外源性凝血途径的活化。同时TFPI还具有抗炎、抑制血管平滑肌增生等生物活性,是目前研究较为火热的蛋白质药物之一。     尽管目前TFPI还没有

    • Tissue Factor Pathway Inhibitor in Thrombosis and Beyond

      of various diseases. In recent years, tissue-factor pathway inhibitor (TFPI), the only endogenous inhibitor of the TF/FVIIa complex, has been characterized biochemically and pharmacologically. Studies in patients have demonstrated that both TF and TFPI

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    人TFPI重组蛋白(TFPI)(Extrinsic pathway inhibitor)(EPI)(Lipoprotein-associated coagulation inhibitor)(LACI)Human Tissue factor pathway inhibitor(TFPI)(Active)蛋白
    ¥888