小鼠肿瘤坏死因子可溶性受体Ⅰ(TNFsR-Ⅰ)ELISA试剂
盒【Mouse Tumor necrosis factor soluble receptor Ⅰ,TNFsR-Ⅰ ELISA Kit】- ￥2500 - 3800
- CUSABIO
- 1.261pg/mL
- 武汉
- CSB-E04737m
- 2025年07月29日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
武汉益普生物科技有限公司
- 检测范围：
1.261pg/mL
- 检测方法：
Sandwich
- 应用：
Signal Transduction
- 适应物种：
Mus musculus (Mouse)
- 样本：
serum, plasma, tissue homogenates
- 规格：
96T/48T
| 规格： | 96T | 产品价格： | ￥3800.0 |
|---|---|---|---|
| 规格： | 48T | 产品价格： | ￥2500.0 |
| Product Name |
Mouse Tumor necrosis factor soluble receptor Ⅰ,TNFsR-Ⅰ ELISA Kit |
| Chinese Name |
小鼠肿瘤坏死因子可溶性受体Ⅰ（TNFsR-Ⅰ）ELISA Kit |
| Code |
CSB-E04737m |
| Alternative Names |
Tnfrsf1a; Tnfr-1; Tnfr1; Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD antigen CD120a |
| Target Name |
tumor necrosis factor receptor superfamily, member 1A |
| Abbreviation |
TNFRSF1A |
| Uniprot No. |
P25118 |
| Species |
Mus musculus (Mouse) |
| Sample Types |
serum, plasma, tissue homogenates |
| Detection Range |
15.625pg/mL-1000pg/mL |
| Sensitivity |
1.261pg/mL |
| Assay Principle |
quantitative |
| Measurement |
Sandwich |
| Assay Time |
1-5h |
| Sample Volume |
50-100ul |
| Detection Wavelength |
450nm |
| Research Area |
Signal Transduction |
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文献和实验Production and Characterization of Receptor-Specific TNF Muteins
Tumor necrosis factor (TNF) is a pleiotropic cytokine with a wide range of biological activities including cytotoxicity, immune-cell proliferation, and mediation of inflammatory responses. Mutational analysis of mature TNF has been facilitated
亲和力，在自然情况下sIL-1BP是IL-1β的抑制剂。可溶性IL-1R（soluble IL-1 receptor,sIL-1R)可有效防止小鼠心脏移植排斥反应，减轻Lewis大鼠的实验性关节炎和过敏性大脑炎。 在T细胞中，CD4阳性细胞亚群IL-1受体表达要高于CD8阳性T细胞亚群。以小鼠胸腺瘤细胞系EL-4为模型，发现IL-1α和IL-1β可结合到相同的高亲和力受体。现已发现联合免疫缺陷病人的T细胞表达IL-1R缺陷，对抗原刺激不发生增殖反应，也不产生IL-2，病人易患机会
Human CD4+CD25highCD127low/neg Regulatory T Cells
25, CD39/CD73, CD62L, CD45RO, CD127, glucocorticoid-induced tumor necrosis factor receptor (GITR), CTLA-4, and the forkhead/winged helix transcription factor (FOXP3), has been used to characterize Tregs. Tregs suppress T effector responses mainly
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