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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉益普生物科技有限公司
- 检测范围:
65pg/mL
- 检测方法:
Sandwich
- 应用:
Signal Transduction
- 适应物种:
Homo sapiens (Human)
- 样本:
serum, plasma, tissue homogenates, urine
- 规格:
96T/48T
| 规格: | 96T | 产品价格: | ¥3600.0 |
|---|---|---|---|
| 规格: | 48T | 产品价格: | ¥2500.0 |
| Product Name |
Human Tumor necrosis factor soluble receptor Ⅰ,TNFsR-ⅠELISA Kit |
| Chinese Name |
人肿瘤坏死因子可溶性受体Ⅰ(TNFsR-Ⅰ)ELISA Kit |
| Code |
CSB-E04736h |
| Alternative Names |
CD120a ELISA Kit; FPF ELISA Kit; MGC19588 ELISA Kit; p55 ELISA Kit; p55-R ELISA Kit; p60 ELISA Kit; TBP1 ELISA Kit; TBPI ELISA Kit; TNF R ELISA Kit; TNF R55 ELISA Kit; TNF-R1 ELISA Kit; TNF-RI ELISA Kit; TNFAR ELISA Kit; TNFR-I ELISA Kit; TNFR1 ELISA Kit; TNFR55 ELISA Kit; TNFR60 ELISA Kit; TNFRI ELISA Kit; TNFRSF1a ELISA Kit; TNR1A_HUMAN ELISA Kit; Tumor necrosis factor receptor 1 ELISA Kit; Tumor necrosis factor receptor superfamily, member 1A ELISA Kit; Tumor necrosis factor receptor type 1 ELISA Kit; Tumor necrosis factor receptor type I ELISA Kit; Tumor necrosis factor-binding protein 1 ELISA Kit |
| Target Name |
tumor necrosis factor receptor superfamily, member 1A |
| Abbreviation |
TNFRSF1A |
| Uniprot No. |
P19438 |
| Species |
Homo sapiens (Human) |
| Sample Types |
serum, plasma, tissue homogenates, urine |
| Detection Range |
78.125pg/mL-5000pg/mL |
| Sensitivity |
65pg/mL |
| Assay Principle |
quantitative |
| Measurement |
Sandwich |
| Assay Time |
1-5h |
| Sample Volume |
50-100ul |
| Detection Wavelength |
450nm |
| Research Area |
Signal Transduction |
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文献和实验Production and Characterization of Receptor-Specific TNF Muteins
Tumor necrosis factor (TNF) is a pleiotropic cytokine with a wide range of biological activities including cytotoxicity, immune-cell proliferation, and mediation of inflammatory responses. Mutational analysis of mature TNF has been facilitated
protein; sST2, soluble ST2; STAT3, signal transducer and activator of transcription 3; TRAF6, tumor necrosis factor receptor-associated factor 6.
分布于EBV转化的B细胞、Raji细胞、巨噬细胞、胎盘、Th2克隆、活化T细胞、PMN和骨髓细胞等。胞膜外区有3个结构域属免疫球蛋白超家族,与IL-1RtⅠ之间有28%氨基酸同源性,穿膜区有更高的同源性,但胞浆区要比Ⅰ型受体短,可能在介导信号传递上有差别。IL-1与IL-1RtⅡ结合后易发生降解而不象IL-1RtⅠ那样发生内化。IL-1RtⅡ经蛋白水解酶水解后可形成可溶性的IL-1结合蛋白(soluble IL-1 binding protein,sIL-1BP),46kDa,与IL-1β有较高
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