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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉益普生物科技有限公司
- 检测范围:
19.5pg/mL
- 检测方法:
Sandwich
- 应用:
Cancer
- 适应物种:
Homo sapiens (Human)
- 样本:
serum, plasma, tissue homogenates
- 规格:
96T/48T
| 规格: | 96T | 产品价格: | ¥3200.0 |
|---|---|---|---|
| 规格: | 48T | 产品价格: | ¥2500.0 |
| Product Name |
Human tissue inhibitors of metalloproteinase 2,TIMP-2 ELISA Kit |
| Chinese Name |
人基质金属蛋白酶抑制因子2(TIMP-2)ELISA Kit |
| Code |
CSB-E04733h |
| Alternative Names |
CSC 21K ELISA Kit; CSC-21K ELISA Kit; CSC21K ELISA Kit; Metalloproteinase inhibitor 2 ELISA Kit; Metalloproteinase inhibitor 2 precursor ELISA Kit; TIMP 2 ELISA Kit; TIMP metallopeptidase inhibitor 2 ELISA Kit; TIMP-2 ELISA Kit; TIMP2 ELISA Kit; TIMP2_HUMAN ELISA Kit; Tissue Inhibitor of Metalloproteinase 2 ELISA Kit; Tissue inhibitor of metalloproteinases 2 ELISA Kit |
| Target Name |
TIMP metallopeptidase inhibitor 2 |
| Abbreviation |
TIMP2 |
| Uniprot No. |
P16035 |
| Species |
Homo sapiens (Human) |
| Sample Types |
serum, plasma, tissue homogenates |
| Detection Range |
78pg/mL-5000pg/mL |
| Sensitivity |
19.5pg/mL |
| Assay Principle |
quantitative |
| Measurement |
Sandwich |
| Assay Time |
1-5h |
| Sample Volume |
50-100ul |
| Detection Wavelength |
450nm |
| Research Area |
Cancer |
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文献和实验(Table 1 ). The enzymatic activity of MMP family members is controlled by a group of inhibitor proteins known as the Tissue Inhibitors of Metalloproteinases (TIMPs), which consist of four family members (Table 2 ). Whereas all four TIMPs can inhibit
Assessing Matrix Metalloproteinase Expression and Activity in Hepatocellular Carcinomas
tissue inhibitors of matrix metalloproteinase (TIMPs). MMPs are involved in situations that require extracellular matrix remodeling, including wound healing, development, inflammation, fibrosis angiogenesis, and tumor invasion (2 –
肉瘤MG-63细胞株和正常成人成骨细胞(hOB)基质金属蛋白酶(MMPs)及其抑制因子(TIMPs)的作用和雌激素缺乏致骨质疏松的发病机制。方法:MMPs和TIMPs蛋白质表达用ELISA和Western Blot检测, mRNA用RT-PCR检测。MMPs活性用明胶酶谱法检测。结果:首次发现E2抑制人成骨肉瘤MG-63细胞株MMP-1 mRNA和蛋白质表达,并且呈剂量依赖关系;10-8M E2抑制hOB MMP-1蛋白质表达;E2对人成骨肉瘤MG-63细胞株MMP-2及TIMP-1 mRNA及蛋白
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