Rabbit anti-Collagen IV Recombinant Monoclonal Antibody(150-5)
抗体英文名:
Rabbit anti-Collagen IV Recombinant Monoclonal Antibody(150-5)
靶点:
-
浓度:
2 mg/mL
应用范围:
Sandwich ELSIA
宿主:
Rabbit
适应物种:
-
保质期:
Store at 4℃ for one year.
抗原来源:
-
目录编号:
-
级别:
-
库存:
现货
供应商:
爱必信(上海)生物科技有限公司
标记物:
-
克隆性:
-
保存条件:
Store at 4℃ for one year.
形态:
液态
亚型:
-
免疫原:
Recombinant protein
规格:
1mg
概述
别名
Collagen type IV (CIV)
宿主
Rabbit
反应种属
Human
应用
Sandwich ELSIA
免疫原
Recombinant protein
性能
形式
Liquid
浓度
2 mg/mL
纯化方法
Protein A affinity column
类型
Monoclonal Antibody
克隆号
150-5
储存/保存方法
Store at 4℃ for one year.
存储溶液
PBS pH7.4, 0.03% Proclin 300
靶标
背景说明
Type IV collagen is a type of collagen that is responsible for providing a scaffold for stability and assembly. It is also predominantly found in extracellular basement membranes. It aids in cell adhesion, migration, survival, expansion, and differentiation. After secretion into the extracellular membrane, these molecules will further interact to form higher molecular organizations. These, along with other proteins, will form unique basement membranes in tissue-specific manners. Through interactions with specific cellular receptors such as integrins, the basement membrane collagen IV networks not only provide structural support to the cells and tissues, but they also affect the biological rate during and after the development. New discoveries keep unraveling information about genetic mutations, biosynthesis, molecular assembly, and network formation of type IV collagen, and this increases the understanding of the critical role of this collagen in health and disease.Liver fibrosis and cirrhosis are associated with the deposition of collagen IV in the liver. Serum Collagen IV concentrations correlate with hepatic tissue levels of collagen IV in subjects with alcoholic liver disease and hepatitis C and fall following successful therapy.