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- 详细信息
- 技术资料
- 抗体名:
Mouse anti-CD28 Recombinant Monoclonal Antibody(AF488 conjugate) (15E8)
- 抗体英文名:
Mouse anti-CD28 Recombinant Monoclonal Antibody(AF488 conjugate) (15E8)
- 靶点:
-
- 浓度:
2 mg/mL
- 应用范围:
FC (Extra): 1:200
- 宿主:
Mouse
- 适应物种:
-
- 保质期:
Store at 4℃ for one year.
- 抗原来源:
-
- 目录编号:
-
- 级别:
-
- 库存:
现货
- 供应商:
爱必信(上海)生物科技有限公司
- 标记物:
-
- 克隆性:
-
- 保存条件:
Store at 4℃ for one year.
- 形态:
液态
- 亚型:
-
- 免疫原:
-
- 规格:
100ul
| 概述 | |
| 别名 | TP44 (Alexa Fluor® 488 conjugate) |
| 宿主 | Mouse |
| 反应种属 | Human |
| 应用 | FC (Extra): 1:200 |
| 性能 | |
| 形式 | Liquid |
| 浓度 | 2 mg/mL |
| 纯化方法 | Protein G affinity column |
| 类型 | Monoclonal Antibody |
| 克隆号 | 15E8 |
| 储存/保存方法 | Store at 4℃ for one year. |
| 存储溶液 | PBS, 0.1% BSA, 0.01% Proclin 300 |
| 靶标 | |
| 背景说明 | CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen-presenting cells (APCs). The CD86 expression on antigen-presenting cells is constitutive (expression is independent of environmental factors). It is generally reported, that CD28 is expressed on 50% of CD8+ T cells and more than 80% CD4+ T cells in human, but during the course of activation some T cells lose this molecule. In general, CD28 is a primary costimulatory molecule for T cell activation. |
| 细胞定位 | Membrane |
| UniProt | P10747 |
Flow cytometric analysis of THP-1 (left) / Jurkat (right) cells labelling CD28 (Alexa Fluor 488 Conjugate) antibody at 1/200 dilution (1 μg) / (red) compared with a Mouse monoclonal IgG (Black) isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Negative control: THP-1
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Mouse anti-CD28 Recombinant Monoclonal Antibody(AF488 conjugate) (15E8)
¥2100







