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- 2025年12月05日
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2713986-17-3
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Topoisomerase inhibitor 2
CAS No. : 2713986-17-3
MCE 国际站：Topoisomerase inhibitor 2
产品活性：Topoisomerase inhibitor 2(18C)是一种细菌拓扑异构酶抑制剂，对多重耐药革兰氏阴性菌表现出强大的广谱活性。
研究领域：Cell Cycle/DNA Damage
作用靶点：Topoisomerase
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文献和实验Analysis of Cleavage Complexes Using Reactive Inhibitor Derivatives
only with the base pairs immediately adjacent to the scissile phosphodiester bond and only in the presence of topoisomerase, providing strong and direct evidence that the DNA substrate forms an important component of the inhibitor binding site.
The Dynamics of DNA Topoisomerase II in Living Cells
Here, we describe methods to prepare a mammalian expression plasmid encoding EGFP fused to the amino-terminus of human DNA topoisomerase IIα (Topo IIα) for use in studying the dynamics of Topo IIα in living cells. In previous studies
Methods to Assay Inhibitors of DNA Gyrase and Topoisomerase IV Activities
DNA gyrase and DNA topoisomerase (topo) IV are the bacterial targets of coumarin and quinolone antimicrobial agents. Widespread resistance to clinically important antibiotics such as beta-lactams and macrolides has stimulated the development
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