A synthesized peptide derived from human Integrin alpha V
内容
500 ug/ml;Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
纯化方式
Affinity-chromatography
浓度
500 ug/ml
产品形态
Liquid
保存条件
12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene(VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.
研究类别
1. Sosnoski DM, Emanuel BS, Hawkins AL, van Tuinen P, Ledbetter DH, Nussbaum RL, Kaos FT, Schwartz E, Phillips D, Bennett JS, et al. (Aug 1988). "Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa". J Clin Invest 81 (6): 1993–8. 2. Fernandez-Ruiz, E., de Villena, F. P.-M., Rodriguez de Cordoba, S., Sanchez-Madrid, F.Regional localization of the human vitronectin receptor alpha-subunit gene (VNRA) to chromosome 2q31-q32.Cytogenet. Cell Genet.62: 26-28, 1993.
[list_product_images]Western blot analysis of Integrin alpha V expression in (1) A549 cell lysate; (2) Mouse spleen lysate; (3) Rat brain lysate.[/list_product_images]