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Monoclonal
human
发货周期:5-7天
9999
博士德生物
WB, IHC
50μl/100μl/150μl
规格: | 50μl | 产品价格: | ¥1060.0 |
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规格: | 100μl | 产品价格: | ¥1780.0 |
规格: | 150μl | 产品价格: | ¥2580.0 |
货号 | MA01199 |
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产品名称 | Anti-VCAM1 Antibody (Clone#OTI4E8) |
基因名 | VCAM1 |
抗体来源 | Mouse |
克隆 | OTI4E8 |
抗体亚型 | Mouse IgG1 |
分子量 | 78.7KD |
免疫原 | Full length human recombinant protein of human VCAM1(NP_001069) produced in HEK293T cell. |
内容 | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500 ug/ml |
产品形态 | Liquid |
保存条件 | Stable for 12 months from date of receipt. Store at -20°C as received. |
背景资料 | This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq] |
研究类别 | 1. Cybulsky, M., Fries, J. W., Williams, A. J., Sultan, P., Eddy, R. L., Byers, M. G., Shows, T. B., Gimbrone, M. A., Jr., Collins, T. The human VCAM1 gene is assigned to chromosome 1p31-p32. (Abstract)Cytogenet. Cell Genet. 58: 1852, 1991.2. Kumar, A. G., Dai, X. Y., Kozak, C. A., Mims, M. P., Gotto, A. M., Ballantyne, C. M. Murine VCAM-1: molecular cloning, mapping, and analysis of a truncated form. J. Immun. 153: 4088-4098, 1994.3. Taylor, J. G., VI, Tang, D. C., Savage, S. A., Leitman, S. F., Heller, S. I., Serjeant, G. R., Rodgers, G. P., Chanock, S. J. Variants in the VCAM1 gene and risk for symptomatic stroke in sickle cell disease. Blood 100: 4303-4309, 2002. |
Uniprot ID | VCAM1: P29534 |
博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
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Western blot (WB): | 1:500~2000 |
Immunohistochemistry in paraffin section (IHC): | 1:150 |
*最佳稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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