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Monoclonal
human, monkey, dog
发货周期:5-7天
9999
博士德生物
WB, IHC, IF
50μl/100μl/150μl
规格: | 50μl | 产品价格: | ¥1060.0 |
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规格: | 100μl | 产品价格: | ¥1780.0 |
规格: | 150μl | 产品价格: | ¥2580.0 |
货号 | MA03651 |
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产品名称 | Anti-ICAM3 / CD50 Antibody (Clone#OTI1E7) |
基因名 | ICAM3 |
抗体来源 | Mouse |
克隆 | OTI1E7 |
抗体亚型 | Mouse IgG1 |
分子量 | 56.4KD |
免疫原 | Full length human recombinant protein of human ICAM3(NP_002153) produced in HEK293T cell. |
内容 | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500 ug/ml |
产品形态 | Liquid |
保存条件 | Stable for 12 months from date of receipt. Store at -20°C as received. |
背景资料 | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq, Jul 2008] |
研究类别 | 1. Bossy, D., Mattei, M.-G., Simmons, D. L. The human intracellular adhesion molecule 3 (ICAM3) gene is located in the 19p13.2-p13.3 region, close to the ICAM1 gene. Genomics 23: 712-713, 1994. 2. Fawcett, J., Holness, C. L. L., Needham, L. A., Turley, H., Gatter, K. C., Mason, D. Y., Simmons, D. L. Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes. Nature 360: 481-484, 1992. 3. Vazeux, R., Hoffman, P. A., Tomita, J. K., Dickinson, E. S., Jasman, R. L., St. John, T., Gallatin, W. M. Cloning and characterization of a new intercellular adhesion molecule ICAM-R. Nature 360: 485-488, 1992. |
Uniprot ID | ICAM3: P32942 |
博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
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Western blot (WB): | 1:400~4000 |
Immunohistochemistry in paraffin section (IHC): | 1:150 |
Immunofluorescence (IF): | 1:100 |
*最佳稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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