GNAI3 polyclonal antibody,GNAI3 polyclonal antibody,GNAI3 polyclonal antibody/GNAI3 polyclonal antibody
产品名称:GNAI3 polyclonal antibody-GNAI3 polyclonal antibody
产品货号:BS8056
产品规格:50ul
应用类型:WB, IHC
保存建议:GNAI3 polyclonal antibody-GNAI3 polyclonal antibodyStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
背景资料:Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Gα subunits have been identified; these include Gs, Gi, Gq and Gα 12/13. The Gi class comprises all the known α subunits that are susceptible to pertussis toxin modifications, including Gα i-1, Gα i-2, Gα i-3, Gα o, Gα t1, Gα t2, Gα z and Gα gust. Of these, the three Gα i subtypes function to open atrial potassium channels.
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