- 询价
- MedChemExpress(MCE)
- 美国
- HY-149244
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Please store the product under the recommended conditions in the Certificate of Analysis.
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- 规格：
询盘
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Nrf2 activator-7
CAS No. : 2456295-39-7
MCE 国际站：Nrf2 activator-7
产品活性：Nrf2 activator-7 (Compound 12b) 是一种有效的 Nrf2 激活剂，可显著激活 Nrf2 信号通路。
研究领域：NF-κB
作用靶点：Keap1-Nrf2
In Vitro: The binding activity of Nrf2 activator-7 to Keap1 has an IC50 value of 85 nM by fluorescence polarization (FP) assay, an IC50 value of 13.1 nM by time-resolved fluorescence energy transfer (TR-FRET) assay, and a Ki value of 4.9 nM.
Nrf2 activator-7 (1, 10, 100 μM; 24 h) increases in the transcription of Nrf2 target genes (GSTM3, HMOX1 and NQO1).
相关产品：ML385 | Resveratrol | Curcumin | 4-Octyl itaconate | Sulforaphane | TBHQ | Luteolin | Dimethyl fumarate | Bardoxolone methyl | Omaveloxolone | KI696 | Brusatol | Ezetimibe | Oltipraz | Carnosol | Hinokitiol | Benzbromarone | ML334 | CBR-470-1 | Mangiferin | Astilbin | CDDO-Im | Pyridoxine hydrochloride | Danshensu | NK-252 | Sappanone A | Nrf2-IN-1 | Safranal | Eriodictyol
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Role of Nrf2-Dependent ARE-Driven Antioxidant Pathway in Neuroprotection
The promoter regions of many detoxification enzymes contain a cis -acting enhancer known as the antioxidant response element (ARE). NF-E2-related factor 2 (Nrf2) is considered as one of the major transcription factors
Nrf2-Target Approaches in Cancer Chemoprevention Mediated by Dietary Phytochemicals
acting by activating the transcriptional factor, nuclear factor-erythroid 2-related factor 2 (Nrf2 or NFE2L2), a basic-region leucine zipper (bZIP) transcription factor that regulates the expression of many phase II detoxifying/antioxidant enzymes
Examining the Endogenous Antioxidant Response Through Immunofluorescent Analysis of Nrf2 in Tissue
conserved mechanism for preventing oxidative stress. NF-E2 (nuclear factor (erythroid-derived 2))-related factor-2 (Nrf2) is the primary regulator of this endogenous antioxidant response. Many diseases that plague human society, ranging from various cancers
技术资料暂无技术资料 索取技术资料
