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- 保存条件:
4°C, sealed storage, away from moisture and light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
1 mg/5 mg
| 规格: | 1 mg | 产品价格: | ¥4240.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥9750.0 |
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NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride
MCE 国际站:NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride
产品活性:NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT(compound I)hydrochloride 是一种拓扑异构酶 I 抑制剂,可通过偶联抗体靶向传递给细胞,具有较好的体内外 ADC 活性。
研究领域:Antibody-drug Conjugate/ADC Related | Cell Cycle/DNA Damage
作用靶点:ADC Cytotoxin | Topoisomerase
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文献和实验Guanidine Hydrochloride Purification of Proteins From SDS
Pepstatin A (2.0 mg/ml)10 ml Leupeptin (1.0 mg/ml)10 ml Aprotinin (5.0 mg/ml)(Protease Inhibitor Cocktail Sigma #P8340)Denaturation Buffer6 M guanidine hydrochloride 57.3 g G-HCl20 mM Hepes 7.9 2 ml 1M Hepes pH 7.910 mM KCl 0.074 g KCl0.5 mM DTT 100 ml 0.5 M
Guanidine Hydrochloride Purification of Proteins From SDS PAGE
(Sigma #P7626) 10 ml Pepstatin A (2.0 mg/ml) 10 ml Leupeptin (1.0 mg/ml) 10 ml Aprotinin (5.0 mg/ml) (Protease Inhibitor Cocktail Sigma #P8340) Denaturation Buffer 6 M guanidine hydrochloride 57.3 g G-HCl 20 mM Hepes 7.9 2 ml 1M Hepes pH 7.9 10 mM
Packed column subcritical and/or supercritical fluid chromatography (p-sub or pSFC) has been used as a powerful chiral separation technique, whereby a mobile phase produces low viscosity, a high diffusion coefficient, and a solvating power. P
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