Laninamivir octanoate辛酸拉尼米韦水合物

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Laninamivir octanoate hydrate

CAS No. : 1233643-88-3

MCE 国际站：Laninamivir octanoate hydrate

产品活性：Laninamivir octanoate hydrate (CS-8958 hydrate)，Laninamivir 的前药，是一种长效的神经氨酸酶 (neuraminidase, NA) 抑制剂，具有抗流感病毒活性。Laninamivir octanoate hydrate 对耐 Oseltamivir 的病毒以及对大流行性流感病毒均具有抗流感活性。

研究领域：Anti-infection

作用靶点：Influenza Virus

In Vitro: Laninamivir octanoate (CS-8958) shows inhibitory activity with an IC₅₀ of 631-1170 nM, 39.2-221 nM and 128 nM to the H1N1 viruses strains, H3N2 viruses strains and H2N2 (A/Singapore/1/57) virus, respectively.

In Vivo: Laninamivir octanoate (CS-8958; 95 μg/kg; intranasal administration; three dose; at 4 h before and 4 h and 17 h postinfection) treatment shows significantly life-prolonging effect in infected model.

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