Yonkenafil,804519-64-0

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Yonkenafil hydrochloride

CAS No. : 804519-64-0

MCE 国际站：Yonkenafil hydrochloride

产品活性：Yonkenafil (Tunodafil) hydrochloride 是一种新型磷酸二酯酶 5 (PDE5) 抑制剂，可有效减少脑梗塞、神经功能缺损、水肿和梗塞区域的神经元损伤。Yonkenafil (Tunodafil) hydrochloride 可能通过调节神经发生来改善认知功能，对阿尔茨海默病具有潜在的研究作用。

研究领域：Metabolic Enzyme/Protease

作用靶点：Phosphodiesterase (PDE)

In Vivo: Yonkenafil (Tunodafil) hydrochloride (4-32 mg/kg, i.v. daily for 7 days) improves behavioral outcomes after stroke and reduces cerebral infarct volume, inhibits neuronal apoptosis, and significantly enhances synaptic function in ischemic brain by modulating the expression of BDNF/TrkB and NGF/TrkA.

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