Recombinant Human PLAU/uPA Protein, His Tag

Recombinant Human PLAU/uPA Pro

tein, His Tag
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  • ¥3885
  • 翌圣生物(Yeasen)已认证
  • 94209ES60
  • 上海
  • 2025年10月16日
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    • 详细信息
    • 技术资料
    • 库存

      现货

    • 英文名

      Recombinant Human PLAU/uPA Protein, His Tag

    • 保质期

      一年

    • 供应商

      翌圣生物科技(上海)股份有限公司

    • 保存条件

      -20度

    • 规格

      100μg

    产品描述
     
    uPA is a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys-Pro-Gly-Arg560-Val561-Val-Gly
    -Gly-Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.
     
    产品性质
     
    Synonyms PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
    Uniprot No. P00749-1
    Source Recombinant Human PLAU/uPA Protein (active form) is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ser21-Leu431, which consists of two chains: Long chain A (Ser21-Phe177) and chain B (Ile179-Leu 431). The long chain A is further cleaved to yield a short chain A (Lys156-Phe 177) and N-terminal fragment (Ser21-Lys155).
    Molecular Weight The protein has a predicted MW of 47.5 kDa. Due to protein lysis and glycosylation, the protein migrates to 24-26 kDa(long chain A), 35-38 kDa(chain B) and 52-60 kDa(long chain A&chain B) based on Tris-Bis PAGE result.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Purity > 95% as determined by SDS-PAGE and HPLC
    Endotoxin 1.0 EU per 1μg of the protein by the LAL method.
    Formulation Lyophilized from 0.22μm filtered solution in 25mM HEPES, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
    Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL` is recommended. Dissolve the lyophilized protein in distilled water.
     
    运输与保存方法
     
    The products are shipped with ice pack and can be stored at -20℃ for 1 year.
    2-7 days, 2 to 8 °C under sterile conditions after reconstitution.
    -6 months, -20 to -80°C under sterile conditions after reconstitution.

    Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
     
    注意事项
     
    1. For your safety and health, please wear lab coats and disposable gloves for operation.
    2. For research use only!
     
    产品数据
     
    Recombinant Human PLAU/uPA Pro
     
    HB221229
     

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