Accelerate your drug discovery program with Kinase Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:
Screen for inhibitors/targets using our unique panel of 75+ assays
Select from IC50 determination and single point concentrations
Receive data within days of compound submission
Perform follow-up studies using the same proteins manufactured in-house
Get questions answered or project guidance in a time-efficient manner
Biochemical Assays
Lipid:
PI3Kα (p110α/p85α)
PI3Kβ (p110β/p85α)
PI3Kδ (p110δ/p85α)
PI3Kγ (p110γ/PIK3R5)
SPHK1
Tyrosine:
Abl
c-Src
FGFR3(V443M)
PDGFRα
Abl-1 (T315I)
EGFR (WT)
FGFR4
PDGFRα(D842Y)
ALK
EGFR (L858R)
Flt1
RET
ALK2
EGFR (T790M)
Flt3
ROS1
AXL
EGFR (L858R, T790M)
FYN
SYK
BTK
EGFR(T790M, C797S,L858R)
HER2
TYK2
cKIT(D816V)
EGFR (murine)
HER4
TYRO3
cKIT(V654A)
EphA2
Jak1
VEGFR2/KDR
cMet
EphB4
Jak2(JH2)
Yes1
cMet (exon 14 Del)
FAK
Jak2(JH2)(V617F)
cMet (WT)
FGFR2
Jak3
cMer
FGFR3(L496V)
FGFR2
CSF1R(FMS)
FGFR3(V443L)
Lck
Serine-Threonine:
AKT
CDK4/CyclinD1
GSK3a
PIM2
Aurora A
CDK4/CyclinD3
GSK3b
PIM3
BRAF
CDK5/p25
HPK1/MAP4K1
RIPK1
BRAF (V600E)
CDK6/CyclinD3
IKKβ
RIPK2
Casein Kinase 1
CDK7/CyclinH1/ MNET1
MNK1
TAK1-TAB1
CDK1/CyclinB1
CDK9/CyclinT1
p38
TBK1
CDK2/CyclinA2
CDK12/CyclinK
PLK1
TNIK
CDK2/CyclinE1
cRAF
PIM1
TTK(Msp1)
Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.