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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现货
- 英文名：
Recombinant Mouse TRANCE/RANK L/TNFSF11
- 保质期：
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 供应商：
爱必信(上海)生物科技有限公司
- 保存条件：
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥1323.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥3881.0 |
| 规格： | 500ug | 产品价格： | ￥13583.0 |
| 规格： | 1mg | 产品价格： | ￥20160.0 |
| 描述 | Recombinant Mouse TNF ligand superfamily member 11 is produced by our expression system and the target gene encoding Lys158-Asp316 is expressed. |
| 别名 | TRANCE蛋白, RANK L蛋白, TNFSF11蛋白;Tumor necrosis factor ligand superfamily member 11,Tnfsf11,Osteoclast differentiation factor,ODF,Osteoprotegerin ligand,OPGL,Receptor activator of nuclear factor kappa-B ligand,RANKL,TNF-related activation-induced cytokine,TRANCE,CD254 |
| 来源 | Escherichia coli. |
| 形态 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| 序列 | QRFSGAPAMMEGSWLDVAQRGKPEAQPFAHLTINAASIPSGSHKVTLSSWYHDRGWAKISNMTLS NGKLRVNQDGFYYLYANICFRHHETSGSVPTDYLQLMVYVVKTSIKIPSSHNLMKGGSTKNWSGN SEFHFYSINVGGFFKLRAGEEISIQVSNPSLLDPDQDATYFGAFKVQDID |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 活性 | Measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells. The ED50 for this effect is 0.2-1 ng/mL. |
| 溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 储存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 背景说明 | Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation. |
| Accession | O35235 |
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文献和实验- α-Linolenic Acid Inhibits RANKL-Induced Osteoclastogenesis In Vitro and Prevents Inflammation In VivoYufeng Deng, Weizhou Li, Yingying Zhang, Jingjing Li, Fangting He, Ke Dong, Zehui Hong, Ruocheng Luo, Xiaofang Pei
Foods. 2023 Feb 03 .
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