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- MedChemExpress(MCE)
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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
4°C, protect from light
- 英文名：
L-822179
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
215874-86-5
- 规格：
1 mg/5 mg/10 mg
| 规格： | 1 mg | 产品价格： | ￥252.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥588.0 |
| 规格： | 10 mg | 产品价格： | ￥924.0 |
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α5IA
CAS No. : 215874-86-5
MCE 国际站：α5IA
产品活性：α5IA(L-822179) 是一种选择性的 α5 GABAA 受体反向激动剂，具有潜在神经保护作用。
研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling
作用靶点：GABA Receptor
In Vitro: α5IA (100 nM, 5 days) can significantly reduce Aβ 1-42-induced cell death in primary mouse hippocampal cultures.
In Vivo: α5IA (5 mg/kg, i.p., once) can sustain restoration of spatial learning ability in Ts65Dn mice, and long-term recognition of spatial memory deficits.
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文献和实验-5.55.15.93.4-3.55.5-5.84.86.05.13.93.7-5.04.6-4.76.5-6.84.8-5.24.7-5.04.0-4.14.55.8-6.03.83-4.411.8-2.75.53.2-3.311.0-11.26.997.077.236.924.6-6.45.64.3-4.54.6-6.29.8-10.14.47-4.575.25.55.45.93.755.36.855.735.351.0左右8.14.97.8 4.584左右
35），CR2（CD21），CR3（CD11b/CD18）,CR4(gp150,90:CD11c/CD18)。其主要特征列于表3-5。此外，尚有其他补体成分的受体，如Ciq受体、C3a受体、C5a受体等。因对其了解不够清楚，不拟介绍。 表3-5 补体受体的特征 名称 别名 CD分类 配体特异性 细胞分布 CR1 IA受体 C3b受体 C4B/C3b受体 CD35 C3bi、C3b C4b、iC4b C3c 红细胞、中性粒细胞 单核细胞、巨噬细胞
Incorporation of Immunomodulators into Plasmid DNA Vaccines
the particular pathogen by the vaccine candidate. The presence of IL-12, IL-15, IL-18, or interferon-gamma (IFN-γ) are critical in the development of Th1 responses that are directed toward cell-mediated immunity (2 ), and the presence of IL-4, IL-5, and IL-10
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