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4°C, sealed storage, away from moisture
- 库存：
货期：1-2天
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MedChemExpress LLC
- CAS号：
58002-62-3
- 规格：
5 mg/10 mg
| 规格： | 5 mg | 产品价格： | ￥3200.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥4800.0 |
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Kainic acid hydrate
CAS No. : 58002-62-3
MCE 国际站：Kainic acid hydrate
产品活性：Kainic acid hydrate 是一种有效的兴奋性毒性剂。Kainic acid hydrate 也是离子型谷氨酸受体亚型的激动剂。Kainic acid hydrate 诱发癫痫发作。
研究领域：GPCR/G Protein | Neuronal Signaling
作用靶点：mGluR
In Vivo: Kainic acid hydrate (5 mg/kg; i.p.; hourly at least 3 h until status epilepticus) induces seizures in rats.
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文献和实验Viral Vector Gene Therapy for Epilepsy
peptides, galanin and neuropeptide Y (NPY), have progressed the furthest. AAV vector-mediated expression and constitutive secretion of galanin essentially prevents electrographic and behavioral seizure activity induced by peripheral kainic acid
Lesion-Induced Vertebrate Models of Alzheimer Dementia
. Surgical procedures and intraparenchymal or intracerebroventricular (i.c.v.) microinjections of toxic substances, such as quinolic, kainic, N -methyl-D -aspartic, ibotenic and quisqualic acids, the specific cholinotoxin AF64, the immunotoxin 192 IgG
Characterization of Wild‐Type Excitatory Amino Acid Ion Channel Receptors
receptors, and the other two types are classified on the basis of the original agonists identified for these sites: kainic acid (kainate; KA) and N?methyl?D?aspartic acid (NMDA). Thus, the three recognized ionotropic receptors are the AMPA, KA and NMDA
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