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Axl/Mer/CSF1R-IN-1
CAS No. : 2394874-60-1
MCE 国际站：Axl/Mer/CSF1R-IN-1
产品活性：Axl/Mer-IN-1 (Compound 1) 是一种 Axl/Mer 受体酪氨酸激酶 (Axl/Mer RTK) 和 CSF1R 抑制剂，Kd 值均小于 0.1 μM。
研究领域：Protein Tyrosine Kinase/RTK
作用靶点：TAM Receptor | c-Fms
In Vitro: Axl/Mer-IN-1 (Compound 1) inhibits cellular Axl activity with an IC50 of <0.5 μM by H1299 Elisa assay. Axl/Mer-IN-1 inhibits cellular CSF1R activity with IC50s of <0.5 μM and <1.0 μM by THP-1 Elisa assay and by M-NFS-60 viability assay, respectively.
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文献和实验Plant DNA methylation analysis by bisulfite genomic sequencing
) at temperature appropriate for used restriction enzyme; Add 0.5ml Tris-buffer-saturated phenol-chroroform, vortex; Centrifuge with Eppendorf 5414 or equivalent at 10000 x g for 2 minutes; Transfer the upper aqueous phase to clean 1.5ml
Whole genome amplification protocol for ChIP-chip
of different factors (E2F family members, KAP1, CtBP2, ZNF217) as well as on histone modifications (H3me3K9, H3me3K27, H3me3K4) (Krig et al., 2007; O'Geen et al., 2007). Another benefit of the WGA amplification method is the ability to perform a second
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