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DM-CO-(CH2)5-SMe
CAS No. : 2243689-84-9
MCE 国际站:DM-CO-(CH2)5-SMe
产品活性:DM-CO-(CH2)5-SMe 是一种抗癌剂,来自抗体活性分子偶联物 (ADC) 代谢产物,对 H1703、H1975、COLO704 和 Colo720E 细胞具有细胞毒性。
研究领域:Metabolic Enzyme/Protease
作用靶点:Drug Metabolite
In Vitro: DM-CO-(CH2)5-SMe (Compound 25 a) (0.00008-30 nM; 5 d) inhibits the viability of H1703, H1975 and COLO704 cells with IC50 values of 2.27 pM, 0.893 pM and 3.04 pM, respectively.
DM-CO-(CH2)5-SMe inhibits the viability of Colo720E cells with an IC50 value of 3 pM.
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