重组人CA125/MUC16 蛋白相关信息: 英文名称 Recombinant human CA125 / MUC16 protein, C-His-Avi (HEK293) 中文名称 重组人CA125/MUC16 蛋白 英文别名 CA 125; CA-125; CA125 ovarian cancer antigen; Cancer antigen 125; FLJ14303; MUC16_HUMAN; MUC 16; MUC16; Mucin 16; MUC-16; Mucin 16 cell surface associated; Mucin16; Ovarian cancer related tumor marker CA125; Ovarian carcinoma antigen CA125; Ovarian cancer-related tumor marker CA125; Recombinant human CA125 / MUC16 protein, C-His-Avi (HEK293) 蛋白细胞定位 细胞膜,分泌型蛋白 分子量 200 浓度 >0.5 mg/ml 储存液 Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. 保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
重组人CA125/MUC16 蛋白
纯度 >95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC 内毒素 <1.0 EU/μg as determined by LAL 重组蛋白-表达系统 HEK293 cell
背景资料:MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators.