英文名称 Recombinant human Angiopoietin-like 3 protein, C-His-Avi (HEK293) / Biotin 中文名称 生物素标记重组人Angiopoietin-like 3蛋白 英文别名 AGNPT5; Ang-5; angiopoietin 5; Angiopoietin-5; Angiopoietin-like Protein 3; angiopoietin-related protein 3; ANGPT5angiopoietin-5; ANGPTL3; FHBL2; Recombinant human Angiopoietin-like 3 protein, C-His-Avi (HEK293) / Biotin 蛋白细胞定位 分泌型蛋白 分子量 49 浓度 >0.5 mg/ml 储存液 Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. 保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
生物素标记重组人Angiopoietin-like 3蛋白
背景资料:Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.