产品分类 重组蛋白 英文名称 Recombinant human Pepsin A-4 / PGA4 protein, His 中文名称 重组人胃蛋白酶原4蛋白 英文别名 Pepsin A-4; PEPA4_HUMAN; PGA4; pepsinogen 4, group I (pepsinogen A); Pepsin A 4; Pepsinogen-4; PGI; Recombinant Human Pepsin A-4 / PGA4 protein, His 蛋白细胞定位 分子量 41.7 浓度 >0.5 mg/ml 储存液 20 mM Tris-HCl (pH=8.0) 保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
重组人胃蛋白酶原4蛋白
背景资料:Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydro/chloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.