产品名称:Human B7-H1 / PD-L1 / CD274 Antibody (Cosibelimab, Research Use)
产品编号:NBR-0563
针对靶点:B7-H1 / PD-L1 / CD274
抗体药商品名:Cosibelimab
抗体药描述:Cosibelimab is a potential best-in-class, high affinity, fully humanized monoclonal antibody of IgG1 subtype that binds directly to PD-L1 and inhibits the PD-L1 interaction with the PD-1 and B7.1 receptors.
Gene Name: CD274
Synonyms: B7-H; B7-H1; B7H1; PD-L1; PDCD1LG1; PDL1
Target Description: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.
Ensembl: ENSG00000120217
Uniprot: Q9NZQ7