产品名称:Human CD27L / CD70 Antibody (Cusatuzumab, Research Use)
产品编号:NBR-0434
针对靶点:CD27L / CD70
抗体药商品名:Cusatuzumab
抗体药描述:Cusatuzumab is designed as a first-in-class, high-affinity anti-CD70 monoclonal antibody with multiple intended mechanisms of action, including Fc-mediated cytotoxicity with enhanced ADCC and inhibition of CD70/CD27 signaling, resulting in killing of malignant cells such as leukemia blasts and stem cells.
Gene Name: CD27L / CD70
Synonyms: CD27L; CD27LG; TNFSF7
Target Description: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Ensembl: ENSG00000125726
Uniprot: P32970