产品名称:Human IL-4RA Antibody (Dupilumab, Research Use)
产品编号:NBR-0227
针对靶点:IL-4RA
抗体药商品名:Dupilumab
抗体药描述:Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis.
Gene Name: IL-4RA
Synonyms: CD124
Target Description: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.
Ensembl: ENSG00000077238
Uniprot: P24394