产品名称:Human PD-L1 Antibody (MDX-1105, Research Use)
产品编号:NBR-0071
针对靶点:PD-L1
抗体药商品名:MDX-1105
抗体药描述:BMS-936559 (MDX-1105) is a PD-1 (PDCD1) human monoclonal antibody, which blocks the binding of PD-L1 (CD274) resulting in a T-cell mediated immune response and possible tumor regression.
Gene Name: PD-L1
Synonyms: CD274; B7H1; PDL1
Target Description: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.
Ensembl: ENSG00000120217
Uniprot: Q9NZQ7