产品名称:Human CD27L / CD70 Antibody (Vorsetuzumab, Research Use)
产品编号:NBR-0020
针对靶点:CD27L / CD70
抗体药商品名:Vorsetuzumab
抗体药描述:Vorsetuzumab mafodotin (SGN-75) is an antibody-drug conjugate (ADC) directed to the protein CD70 designed for the treatment of cancer.[1] It is a humanized monoclonal antibody, vorsetuzumab, conjugated with noncleavable monomethyl auristatin F (MMAF), a cytotoxic agent.
Gene Name: CD27L / CD70
Synonyms: CD27L; CD27LG; TNFSF7
Target Description: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Ensembl: ENSG00000125726
Uniprot: P32970