产品名称:Human CCR2 Antibody (Plozalizumab, Research Use)
产品编号:NBR-0119
针对靶点:CCR2
抗体药商品名:Plozalizumab
抗体药描述:Plozalizumab (INN; hu1D9) is a humanized monoclonal antibody designed for the treatment of diabetic nephropathy and arteriovenous graft patency.
Gene Name: CCR2
Synonyms: CC-CKR-2; MCP-1-R; CMKBR2; CD192; CKR2
Target Description: CCR2 (C-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CCR2 include Human Immunodeficiency Virus Type 1 and Acquired Immunodeficiency Syndrome. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR5.
Ensembl: ENSG00000121807
Uniprot: P41597