DER-4; DER4; FIT 1; Growth stimulation expressed gene 2; homolog of mouse growth stimulation-expressed; Il1rl1; IL33R; ILRL1_HUMAN; Interleukin 1 receptor like 1; interleukin 1 receptor related protein; Interleukin-1 receptor-like 1; Ly84; Lymphocyte antigen 84; Protein ST2; ST2; ST2L; ST2V; Ste2; Suppressor of tumorigenicity 2; T1; T1 protein; Recombinant human ST2 protein, His
理论分子量
36kDa
检测分子量
40 kDa
性 状
Lyophilized or Liquid
浓 度
>0.5 mg/ml
物 种
Human
序 列
19-328/556
纯 度
>95% as determined by SDS-PAGE
纯化方法
AC
内毒素
Not analyzed
表达系统
E.coli
活性
Yes
标签
His
缓 冲 液
20 mM Tris-HCl (pH=7.2) with 1 M Urea
保存条件
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
重组人生长刺激表达基因2蛋白
产品介绍:ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.