TGF-beta receptor type-2; TGF beta R2; TGFBR2; AAT 3; AAT3; FAA 3; FAA3; HNPCC6; MFS 2; MFS2; RIIC; TAAD 2; TAAD2; TbetaR II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta type II receptor; TGFB R2; TGFbeta RII; TGFBR 2; TGFR 2; TGFR2; Transforming growth factor beta receptor II; Transforming growth factor beta receptor type II. ;Recombinant human TGFBR2 protein, C-His (HEK293)
理论分子量
19.2kDa
检测分子量
23-38 kDa
性 状
Lyophilized or Liquid
浓 度
>0.5 mg/ml
物 种
Human
序 列
23-159/567
纯 度
>90% as determined by SDS-PAGE
纯化方法
AC
内毒素
Not analyzed
表达系统
HEK293 cell
活性
Not tested
标签
C-His
缓 冲 液
PBS (pH=7.4)
保存条件
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
重组人转移生长因子β受体2蛋白
产品介绍:This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.