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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
瓶身
- 保质期:
coa
- 英文名:
SIGMA
- 库存:
999
- 供应商:
麦格生物
- 规格:
WH0004724M1-100UG
说明
一般描述
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. (provided by RefSeq)
免疫原
NDUFS4 (NP_002486, 66 a.a. ~ 175 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GVPEEHIKTRKVRIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWASTADPLSNMVLTFSTKEDAVSFAEKNGWSYDIEERKVPKPKSKSYGANFSWNKRTRVSTK
外形
Solution in phosphate buffered saline, pH 7.4

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文献和实验Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver.
Muyu Yu et al.
International journal of biological sciences, 17(7), 1693-1707 (2021-05-18)
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