Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (Mouse) Monoclonal Antibody - 200-301-A33,抗甘油醛-3-磷酸脱氢酶(GAPDH)(小鼠)单克隆抗体-200-301-A33,抗甘油醛-3-磷酸脱氢酶(GAPDH)(小鼠)单克隆抗体-200-301-A33,Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (Mouse) Monoclonal Antibody - 200-301-A33
产品名称:抗甘油醛-3-磷酸脱氢酶(GAPDH)(小鼠)单克隆抗体-200-301-A33-Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (Mouse) Monoclonal Antibody - 200-301-A33
产品货号:200-301-A33
产品规格:100ug
应用类型:ELISA,Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,
保存建议:抗甘油醛-3-磷酸脱氢酶(GAPDH)(小鼠)单克隆抗体-200-301-A33-Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (Mouse) Monoclonal Antibody - 200-301-A33Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
背景资料:GAPDH Loading Control Monoclonal Antibody detects Glyceraldehyde-3-Phosphate Dehydrogenase. GAPDH is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. Because GAPDH is a protein expressed in large amounts and which is required at all times for important "house keeping" functions, levels of GAPDH mRNA are often measured and used as standards in studies of mRNA expression. Increasingly, scientists are making use of specific antibodies to GAPDH in comparable studies of levels of protein expression. Apart from a role in glycolysis, GAPDH may have other roles such as in the activation of transcription. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease, and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations with actin and tubulin have also been reported. The protein may also have a role in the regulation of apoptosis, and interestingly migrates from the cytoplasm into the nucleus when cells become apoptotic. Anti-GAPDH antibody is widely used as a loading control for western blotting experiments, allowing comparison between the level of this protein and others in a cell or tissue and is ideal for Neuroscience, Cell Signaling and Cancer Research.
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