Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
产品名称:BAX重组蛋白-GST融合蛋白-009-001-R47S-【干冰】BAX recombinant protein-GST fusion protein-009-001-R47S
产品货号:009-001-R47S
产品规格:20ug
来源宿主:该BAX重组蛋白-GST融合蛋白-009-001-R47S的详细信息查看Rockland提供的产品说明。
保存建议:BAX重组蛋白-GST融合蛋白-009-001-R47S-【干冰】BAX recombinant protein-GST fusion protein-009-001-R47SStore product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
背景资料:BAX is a proapoptotic protein of the BCL2 protein family. BAX forms a heterodimer with BCL2 and functions as an apoptotic activator. BAX interacts with and increases the opening of the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in the mitochondrial membrane potential and the release of cytochrome c (1). The expression of BAX gene is regulated by the tumor suppressor p53 and BAX has been shown to be involved in p53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene (2). BAX Protein is ideal for investigators involved in Signaling Proteins, Apoptosis Proteins, AKT/PKB Pathway, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, and Neurobiology research.
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