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文献和实验The human CYP1 family consists of at least three proteins, CYP1A1, CYP1A2, and CYP1B1 (1 ), CYP1A1 is absent or present at very low levels in human liver (2 , 3 ), but its expression is readily detectable in lung (4 , 5 ). By contrast
ALDH as a Marker for Enriching Tumorigenic Human Colonic Stem Cells
Aldehyde dehydrogenase (ALDH) can be used as a marker to isolate, propagate, and track normal and cancerous human colon stem cells. To determine their tumorigenic potential, tissues obtained from proximal (normal counterpart) and distal
In Vitro Identification of UDP-Glucuronosyltransferases (UGTs) Involved in Drug Metabolism
in the prediction of adverse reactions resulting from drug-drug interactions or genetic polymorphism. An integrated approach is proposed for UGT reaction phenotyping using recombinant enzymes and human liver microsomes. Described methods include screening
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