- ￥1200
- 万类生物
- 中国
- WL02790
- 2025年12月18日
- WB,IHC,IF
- 兔
- HMR
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- 详细信息
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
多克隆
- 标记物：
无
- 适应物种：
HMR
- 抗原来源：
兔
- 供应商：
万类生物
- 宿主：
兔
- 应用范围：
WB,IHC,IF
- 抗体英文名：
VDAC1 antibody
- 规格：
50μl(＞50μg)
产品概述
Voltage-dependent anion-selective channel 1 (VDAC-1) is a beta barrel protein that in humans is encoded by the VDAC1 gene located on chromosome 5. VDAC1 is involved in cell metabolism by transporting ATP and other small metabolites across the outer mitochondrial membrane (OMM) allowing regulation of the TCA cycle and, by extension, reactive oxygen species (ROS) production. VDAC1 has been shown to interact with Amyloid β (Aβ) leading to increased conductance of the channel and eventually apoptosis of the cell. VDAC1 acts as a scaffold for many proteins as well as allows for the flux of ions and metabolites through interactions within the pore.
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