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- 详细信息
- 技术资料
- 亚型:
IgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
多克隆
- 标记物:
无
- 适应物种:
HMR
- 保质期:
一年
- 抗原来源:
兔
- 供应商:
万类生物
- 宿主:
兔
- 应用范围:
WB,IHC,IF
- 浓度:
>1 mg/ml
- 靶点:
IL6
- 抗体英文名:
IL6 antibody
- 抗体名:
IL6 抗体
- 规格:
50μl(>50μg)
产品概述
IL6(Interleukin-6) is a multifunctional protein, that plays critical roles in host defense, immune response and hematopoiesis. IL6 is constitutively expressed by epidermal Langerhans cells and its expression is induced in stimulated keratinocytes. IL6 induces proliferation or differentiation in many cell types including B cells, thymocytes and T cells. IL6, in concert with TGF-β, is important for developing Th17 responses. IL6 binds to IL6Rα and through this association induces gp130 homodimerization. Research studies have shown that IL6, through increasing expression of proangiogenic VEGF, may also contribute to metastatic breast cancer.
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