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- 详细信息
- 技术资料
- 亚型:
IgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
多克隆
- 标记物:
无
- 适应物种:
HMR
- 保质期:
一年
- 抗原来源:
兔
- 供应商:
万类生物
- 宿主:
兔
- 应用范围:
WB
- 浓度:
>1 mg/ml
- 靶点:
c-fos
- 抗体英文名:
c-Fos antibody
- 抗体名:
c-fos 抗体
- 规格:
50μl(>50μg)
产品概述
In the fields of molecular biology and genetics, c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos. Fos proteins dimerize with Jun proteins (c-Jun, JunB, and JunD) to form Activator Protein-1 (AP-1), a transcription factor that binds to TRE/AP-1 elements and activates transcription. c-fos plays an important role in many cellular functions and has been found to be overexpressed in a variety of cancers. Expression of c-fos is an indirect marker of neuronal activity because c-fos is often expressed when neurons fire action potentials. Upregulation of c-fos mRNA in a neuron indicates recent activity.
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